D. Lee Alekel
Professor /
Interim Associate Director, NWRC |
Education: Ph.D., Nutrition, University of
Illinois, 1993
Interests: The relationship of body composition,
physical activity, and nutrient intake to bone mineral density
and osteoporotic risk in women; the effect of the menopausal transition
and reproductive function/menstrual dysfunction on bone and body
composition; and the assessment of nutritional status and body
composition in health and disease.
Office: 1115 Human Nutritional Sciences Building
Phone: (515) 294-3552
Fax: (515) 294-5390
Email: alekel@iastate.edu
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Publications:
Books/Book Chapters
- Alekel DL. Skeletal Effects of Soy Isoflavones in Humans: Bone Mineral Density and Bone Markers. In: Handbook of Nutraceuticals and Functional Foods. Second edition. Eds: Robert E.C. Wildman. CRC Press LLC. 2006.
- Alekel DL, Matvienko O: Influence of lifestyle choices on calcium homeostasis: Smoking, alcohol, and hormone therapies. Part IV, Chapter 13. In: Calcium in Human Health. First Edition. CM Weaver, RP Heaney, eds. Humana Press Inc. Totowa, NJ. 2006.
- Messina M, Ho S, Alekel DL. Skeletal benefits of soy isoflavones: A review of the clinical trial and epidemiologic data. Curr Opin Clin Nutr Metab Care 7:649-658, 2004.
- Birt, D.F., Hendrich, S., Anthony, M. and D.L.
Alekel. 2004. Soybeans and the prevention of chronic human disease.
Soybeans: Improvement, Production and Uses. J. Specht and R. Boerma,
Eds. 3rd edition American Society of Agronomy, Madison WI. pp 1047-1117.
- Anderson, J.J.B. and D.L. Alekel. 2002. Skeletal
Effects of Phytoestrogens in Humans: Bone Mineral Density and Bone
Markers. In: GS Gilani GS, Anderson JJB (eds), Phytoestrogens and
Health. American Oil Chemists' Society Press, Champaign, IL: pp 341-353.
- Anthony, M.S., Anderson, J.J.B. and D.L. Alekel.
2002. Association between soy and/or isoflavones and bone: evidence
from epidemiologic studies. In: Gilani GS, Anderson JJB (eds), Phytoestrogens
and Health. American Oil Chemists' Society Press, Champaign, IL: pp
331-340.
Journal Articles
- Ritland LM, Alekel DL, Matvienko O, Hanson KB, Stewart JW, Hanson LN, Reddy MB, Van Loan M, Genschel U. Relationship of centrally-located fat mass and lean mass to circulating leptin, adiponectin, ghrelin, and insulin in healthy postmenopausal women. Europ J Endocrin 158:889-897, 2008.
- Perry CD, Alekel DL, Ritland L, Bhupathiraju SN, Stewart JW, Hanson LN, Matvienko O, Kohut M, Reddy MB, Van Loan MD, Genschel U. Relationship of centrally-located body fat to acute phase proteins and proinflammatory cytokines in healthy postmenopausal women. Menopause 15(4):619-627, 2008
- Shedd KM, Hanson KB, Alekel DL, Schiferl DJ, Hanson LN, Van Loan MD. Quantifying leisure physical activity and its relation to bone density and strength. Med Sci Sports Exerc. 39(12):2189-2198, 2007.
- Bhupathiraju SN, Alekel DL, Stewart JW, Hanson LN, Shedd KM, Reddy MB, Hanson KB, Van Loan MD, Genschel U, Koehler KJ. Relationship of circulating total homocysteine and C-reactive protein to trabecular bone in postmenopausal women. J Clin Densit 10(4):395-403, 2007.
- Engelman* HM, Alekel, D.L., Hanson LN, Kanthasamy AG, Reddy AM.
Blood lipid and oxidative stress responses to soy isoflavones and
phytic acid in postmenopausal women. Am J Clin Nutr 81:590-596, 2005.
[*Barwick as MS student]
- Zheng, Y.L., Hu, J., Murphy, P.A., Alekel, D.L., Franke, W.D. and
S. Hendrich. 2003. Rapid gut transit time and slow fecal isoflavone
disappearance phenotype are associated with greater genistein bioavailability
in women. J Nutr. 133:3110-3116.
- Moeller, L.E., Peterson, C.T., Hanson, K.B., Dent, S.B., Lewis,
D., King, D. and D.L. Alekel. 2003. Isoflavone-rich soy protein prevents
loss of hip lean mass, but does not prevent the shift in regional
fat distribution in menopausal women. Menopause. 10(4):322-331.
- Swain, J.H., Alekel, D.L., Dent, S.B., Peterson, C.T. and M.B.
Reddy. 2002. Iron indices and total antioxidant status in response
to soy protein intake in perimenopausal women. Am J Clin Nutr. 76:165-171.
- Alekel, D.L., Peterson, C.T., Werner, R.K., Mortillaro, E., Ahmed,
N., and S.C. Kukreja. 2002. Frame size, ethnicity, lifestyle, and
biologic contributors to areal and volumetric lumbar spine bone mineral
density in Indian/Pakistani and American Caucasian premenopausal women.
J Clin Densit 5:175-186.
- Matvienko, O., Lewis, D.S., Swanson, M., Arndt, B., Rainwater,
D.L., Stewart, J.W. and D.L. Alekel. 2002. A single daily dose of
soybean plant sterols in ground beef decreases serum total and low-density
lipoprotein cholesterol in young mildly hypercholesterolemic men.
Am J Clin Nutr. 76:57-64.
- Dent, S.B., Peterson, C.T., Brace, L.D., Swain, J.H., Reddy, M.B.,
Hanson, K.B. and D.L. Alekel. 2001. Circulating lipids and lipoproteins
or coagulation and fibrinolytic factors do not change in response
to soy protein intake in perimenopausal women. J Nutr. 131:2280-2287.
- St.Germain, A., Peterson, C.T., Robinson, J. and D.L. Alekel. 2001.
Effect of isoflavone-rich soy protein isolate on menopausal symptoms
in perimenopausal women. Menopause. 8(1):17-26.
- Alekel, D.L., St.Germain, A., Peterson, C.T., Hanson, K.B., Stewart,
J.W. and T. Toda. 2000. Isoflavone-rich soy protein isolate attenuates
bone loss in the lumbar spine of perimenopausal women. Am J Clin Nutr.
72:844-852.
- Alekel, D.L., Mortillaro, E., Hussain, E.A., West, B., Ahmed, N.,
Peterson, C.T., Werner, R.K., Arjmandi, B.H. amd S.C. Kukreja. 1999.
Lifestyle and biologic contributors to proximal femur bone mineral
density and hip axis length in two distinct ethnic groups of premenopausal
women. Osteoporos Int. 9:327-338.
- Kamath, S.K., Hussain, E.A., Amin, D., Mortillaro, E., West, B.,
Peterson, C.T., Aryee, F., Murillo, G. and D.L. Alekel. 1999. Cardiovascular
disease risk factors in two distinct ethnic groups: Indian and Pakistani
compared with American premenopausal women. Am J Clin Nutr. 69:621-631.
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