Iowa State University
College of Human Sciences and College of Agriculture College of Human Sciences College of Agriculture


D. Lee Alekel

  D. Lee Alekel Professor /
Interim Associate Director, NWRC

 

    Education: Ph.D., Nutrition, University of Illinois, 1993

    Interests: The relationship of body composition, physical activity, and nutrient intake to bone mineral density and osteoporotic risk in women; the effect of the menopausal transition and reproductive function/menstrual dysfunction on bone and body composition; and the assessment of nutritional status and body composition in health and disease.

    Office: 1115 Human Nutritional Sciences Building
    Phone: (515) 294-3552
    Fax: (515) 294-5390
    Email: alekel@iastate.edu

Publications:

Books/Book Chapters
  • Alekel DL. Skeletal Effects of Soy Isoflavones in Humans:  Bone Mineral Density and Bone Markers. In:  Handbook of Nutraceuticals and Functional Foods. Second edition. Eds:  Robert E.C. Wildman. CRC Press LLC. 2006.
  • Alekel DL, Matvienko O:  Influence of lifestyle choices on calcium homeostasis:  Smoking, alcohol, and hormone therapies.  Part IV, Chapter 13.  In:  Calcium in Human Health.  First Edition.  CM Weaver, RP Heaney, eds. Humana Press Inc.  Totowa, NJ.  2006.
  • Messina M, Ho S, Alekel DL. Skeletal benefits of soy isoflavones:  A review of the clinical trial and epidemiologic data. Curr Opin Clin Nutr Metab Care 7:649-658, 2004.
  • Birt, D.F., Hendrich, S., Anthony, M. and D.L. Alekel. 2004. Soybeans and the prevention of chronic human disease. Soybeans: Improvement, Production and Uses. J. Specht and R. Boerma, Eds. 3rd edition American Society of Agronomy, Madison WI. pp 1047-1117.
  • Anderson, J.J.B. and D.L. Alekel. 2002. Skeletal Effects of Phytoestrogens in Humans: Bone Mineral Density and Bone Markers. In: GS Gilani GS, Anderson JJB (eds), Phytoestrogens and Health. American Oil Chemists' Society Press, Champaign, IL: pp 341-353.
  • Anthony, M.S., Anderson, J.J.B. and D.L. Alekel. 2002. Association between soy and/or isoflavones and bone: evidence from epidemiologic studies. In: Gilani GS, Anderson JJB (eds), Phytoestrogens and Health. American Oil Chemists' Society Press, Champaign, IL: pp 331-340.
Journal Articles
  • Ritland LM, Alekel DL, Matvienko O, Hanson KB, Stewart JW, Hanson LN, Reddy MB, Van Loan M, Genschel U.  Relationship of centrally-located fat mass and lean mass to circulating leptin, adiponectin, ghrelin, and insulin in healthy postmenopausal women.  Europ J Endocrin 158:889-897, 2008.
  • Perry CD, Alekel DL, Ritland L, Bhupathiraju SN, Stewart JW, Hanson LN, Matvienko O, Kohut M, Reddy MB, Van Loan MD, Genschel U.  Relationship of centrally-located body fat to acute phase proteins and proinflammatory cytokines in healthy postmenopausal women.  Menopause 15(4):619-627, 2008
  • Shedd KM, Hanson KB, Alekel DL, Schiferl DJ, Hanson LN, Van Loan MD. Quantifying leisure physical activity and its relation to bone density and strength.  Med Sci Sports Exerc.  39(12):2189-2198, 2007.
  • Bhupathiraju SN, Alekel DL, Stewart JW, Hanson LN, Shedd KM, Reddy MB, Hanson KB, Van Loan MD, Genschel U, Koehler KJ.  Relationship of circulating total homocysteine and C-reactive protein to trabecular bone in postmenopausal women. J Clin Densit  10(4):395-403, 2007.
  • Engelman* HM, Alekel, D.L., Hanson LN, Kanthasamy AG, Reddy AM. Blood lipid and oxidative stress responses to soy isoflavones and phytic acid in postmenopausal women. Am J Clin Nutr 81:590-596, 2005. [*Barwick as MS student]
  • Zheng, Y.L., Hu, J., Murphy, P.A., Alekel, D.L., Franke, W.D. and S. Hendrich. 2003. Rapid gut transit time and slow fecal isoflavone disappearance phenotype are associated with greater genistein bioavailability in women. J Nutr. 133:3110-3116.
  • Moeller, L.E., Peterson, C.T., Hanson, K.B., Dent, S.B., Lewis, D., King, D. and D.L. Alekel. 2003. Isoflavone-rich soy protein prevents loss of hip lean mass, but does not prevent the shift in regional fat distribution in menopausal women. Menopause. 10(4):322-331.
  • Swain, J.H., Alekel, D.L., Dent, S.B., Peterson, C.T. and M.B. Reddy. 2002. Iron indices and total antioxidant status in response to soy protein intake in perimenopausal women. Am J Clin Nutr. 76:165-171.
  • Alekel, D.L., Peterson, C.T., Werner, R.K., Mortillaro, E., Ahmed, N., and S.C. Kukreja. 2002. Frame size, ethnicity, lifestyle, and biologic contributors to areal and volumetric lumbar spine bone mineral density in Indian/Pakistani and American Caucasian premenopausal women. J Clin Densit 5:175-186.
  • Matvienko, O., Lewis, D.S., Swanson, M., Arndt, B., Rainwater, D.L., Stewart, J.W. and D.L. Alekel. 2002. A single daily dose of soybean plant sterols in ground beef decreases serum total and low-density lipoprotein cholesterol in young mildly hypercholesterolemic men. Am J Clin Nutr. 76:57-64.
  • Dent, S.B., Peterson, C.T., Brace, L.D., Swain, J.H., Reddy, M.B., Hanson, K.B. and D.L. Alekel. 2001. Circulating lipids and lipoproteins or coagulation and fibrinolytic factors do not change in response to soy protein intake in perimenopausal women. J Nutr. 131:2280-2287.
  • St.Germain, A., Peterson, C.T., Robinson, J. and D.L. Alekel. 2001. Effect of isoflavone-rich soy protein isolate on menopausal symptoms in perimenopausal women. Menopause. 8(1):17-26.
  • Alekel, D.L., St.Germain, A., Peterson, C.T., Hanson, K.B., Stewart, J.W. and T. Toda. 2000. Isoflavone-rich soy protein isolate attenuates bone loss in the lumbar spine of perimenopausal women. Am J Clin Nutr. 72:844-852.
  • Alekel, D.L., Mortillaro, E., Hussain, E.A., West, B., Ahmed, N., Peterson, C.T., Werner, R.K., Arjmandi, B.H. amd S.C. Kukreja. 1999. Lifestyle and biologic contributors to proximal femur bone mineral density and hip axis length in two distinct ethnic groups of premenopausal women. Osteoporos Int. 9:327-338.
  • Kamath, S.K., Hussain, E.A., Amin, D., Mortillaro, E., West, B., Peterson, C.T., Aryee, F., Murillo, G. and D.L. Alekel. 1999. Cardiovascular disease risk factors in two distinct ethnic groups: Indian and Pakistani compared with American premenopausal women. Am J Clin Nutr. 69:621-631.
Food Science and Human Nutrition