D. Lee Alekel
Professor /
Interim Associate Director, NWRC |
Education: Ph.D., Nutrition, University of
Illinois, 1993
Interests: The relationship of body composition,
physical activity, and nutrient intake to bone mineral density
and osteoporotic risk in women; the effect of the menopausal transition
and reproductive function/menstrual dysfunction on bone and body
composition; and the assessment of nutritional status and body
composition in health and disease.
Office: 1115 Human Nutritional Sciences Building
Phone: (515) 294-3552
Fax: (515) 294-5390
Email: alekel@iastate.edu
|
Publications:
Books/Book Chapters
- Alekel DL. Skeletal Effects of Soy Isoflavones in Humans: Bone Mineral Density and Bone Markers. In: Handbook of Nutraceuticals and Functional Foods. Second edition. Eds: Robert E.C. Wildman. CRC Press LLC. 2006.
- Alekel DL, Matvienko O: Influence of lifestyle choices on calcium homeostasis: Smoking, alcohol, and hormone therapies. Part IV, Chapter 13. In: Calcium in Human Health. First Edition. CM Weaver, RP Heaney, eds. Humana Press Inc. Totowa, NJ. 2006.
- Messina M, Ho S, Alekel DL. Skeletal benefits of soy isoflavones: A review of the clinical trial and epidemiologic data. Curr Opin Clin Nutr Metab Care 7:649-658, 2004.
- Birt, D.F., Hendrich, S., Anthony, M. and D.L.
Alekel. 2004. Soybeans and the prevention of chronic human disease.
Soybeans: Improvement, Production and Uses. J. Specht and R. Boerma,
Eds. 3rd edition American Society of Agronomy, Madison WI. pp 1047-1117.
- Anderson, J.J.B. and D.L. Alekel. 2002. Skeletal
Effects of Phytoestrogens in Humans: Bone Mineral Density and Bone
Markers. In: GS Gilani GS, Anderson JJB (eds), Phytoestrogens and
Health. American Oil Chemists' Society Press, Champaign, IL: pp 341-353.
- Anthony, M.S., Anderson, J.J.B. and D.L. Alekel.
2002. Association between soy and/or isoflavones and bone: evidence
from epidemiologic studies. In: Gilani GS, Anderson JJB (eds), Phytoestrogens
and Health. American Oil Chemists' Society Press, Champaign, IL: pp
331-340.
Journal Articles
-
Deardorff B, Alekel DL, Ritland LM, Hanson LN, Genschel U, Reddy MB. Association among oxidative stress, iron indices, and central adiposity in healthy postmenopausal women. Journal of Women’s Health. In Press. Anticipated publication: 2009
- Ritland LM, Alekel DL, Matvienko O, Hanson KB, Stewart JW, Hanson LN, Reddy MB, Van Loan M, Genschel U. Relationship of centrally-located fat mass and lean mass to circulating leptin, adiponectin, ghrelin, and insulin in healthy postmenopausal women. Europ J Endocrin 158:889-897, 2008.
- Perry CD, Alekel DL, Ritland L, Bhupathiraju SN, Stewart JW, Hanson LN, Matvienko O, Kohut M, Reddy MB, Van Loan MD, Genschel U. Relationship of centrally-located body fat to acute phase proteins and proinflammatory cytokines in healthy postmenopausal women. Menopause 15(4):619-627, 2008
- Shedd KM, Hanson KB, Alekel DL, Schiferl DJ, Hanson LN, Van Loan MD. Quantifying leisure physical activity and its relation to bone density and strength. Med Sci Sports Exerc. 39(12):2189-2198, 2007.
- Bhupathiraju SN, Alekel DL, Stewart JW, Hanson LN, Shedd KM, Reddy MB, Hanson KB, Van Loan MD, Genschel U, Koehler KJ. Relationship of circulating total homocysteine and C-reactive protein to trabecular bone in postmenopausal women. J Clin Densit 10(4):395-403, 2007.
- Engelman* HM, Alekel, D.L., Hanson LN, Kanthasamy AG, Reddy AM.
Blood lipid and oxidative stress responses to soy isoflavones and
phytic acid in postmenopausal women. Am J Clin Nutr 81:590-596, 2005.
[*Barwick as MS student]
- Zheng, Y.L., Hu, J., Murphy, P.A., Alekel, D.L., Franke, W.D. and
S. Hendrich. 2003. Rapid gut transit time and slow fecal isoflavone
disappearance phenotype are associated with greater genistein bioavailability
in women. J Nutr. 133:3110-3116.
- Moeller, L.E., Peterson, C.T., Hanson, K.B., Dent, S.B., Lewis,
D., King, D. and D.L. Alekel. 2003. Isoflavone-rich soy protein prevents
loss of hip lean mass, but does not prevent the shift in regional
fat distribution in menopausal women. Menopause. 10(4):322-331.
- Swain, J.H., Alekel, D.L., Dent, S.B., Peterson, C.T. and M.B.
Reddy. 2002. Iron indices and total antioxidant status in response
to soy protein intake in perimenopausal women. Am J Clin Nutr. 76:165-171.
- Alekel, D.L., Peterson, C.T., Werner, R.K., Mortillaro, E., Ahmed,
N., and S.C. Kukreja. 2002. Frame size, ethnicity, lifestyle, and
biologic contributors to areal and volumetric lumbar spine bone mineral
density in Indian/Pakistani and American Caucasian premenopausal women.
J Clin Densit 5:175-186.
- Matvienko, O., Lewis, D.S., Swanson, M., Arndt, B., Rainwater,
D.L., Stewart, J.W. and D.L. Alekel. 2002. A single daily dose of
soybean plant sterols in ground beef decreases serum total and low-density
lipoprotein cholesterol in young mildly hypercholesterolemic men.
Am J Clin Nutr. 76:57-64.
- Dent, S.B., Peterson, C.T., Brace, L.D., Swain, J.H., Reddy, M.B.,
Hanson, K.B. and D.L. Alekel. 2001. Circulating lipids and lipoproteins
or coagulation and fibrinolytic factors do not change in response
to soy protein intake in perimenopausal women. J Nutr. 131:2280-2287.
- St.Germain, A., Peterson, C.T., Robinson, J. and D.L. Alekel. 2001.
Effect of isoflavone-rich soy protein isolate on menopausal symptoms
in perimenopausal women. Menopause. 8(1):17-26.
- Alekel, D.L., St.Germain, A., Peterson, C.T., Hanson, K.B., Stewart,
J.W. and T. Toda. 2000. Isoflavone-rich soy protein isolate attenuates
bone loss in the lumbar spine of perimenopausal women. Am J Clin Nutr.
72:844-852.
- Alekel, D.L., Mortillaro, E., Hussain, E.A., West, B., Ahmed, N.,
Peterson, C.T., Werner, R.K., Arjmandi, B.H. amd S.C. Kukreja. 1999.
Lifestyle and biologic contributors to proximal femur bone mineral
density and hip axis length in two distinct ethnic groups of premenopausal
women. Osteoporos Int. 9:327-338.
- Kamath, S.K., Hussain, E.A., Amin, D., Mortillaro, E., West, B.,
Peterson, C.T., Aryee, F., Murillo, G. and D.L. Alekel. 1999. Cardiovascular
disease risk factors in two distinct ethnic groups: Indian and Pakistani
compared with American premenopausal women. Am J Clin Nutr. 69:621-631.
|