Iowa State University
College of Human Sciences and College of Agriculture College of Human Sciences College of Agriculture


Ruth MacDonald

  Ruth MacDonald image
Professor/Department Chair

     

    Education: Ph.D., Nutrition/Food Science, University of Minnesota, 1985

    Interests: Identify factors in foods that reduce the incidence or progression of cancer.

    Office: 2312 Food Sciences Building
    Phone: (515) 294-5991
    Fax: (515) 294-8181
    Email: ruthmacd@iastate.edu

    Research

Publications:

  • Fountain ED, Mao J, Whyte JJ, Mueller KE, Ellersieck MR, Will MJ, Roberts RM, MacDonald RS, Rosenfeld CS. Effects of Diets Enriched in Omega-3 and Omega-6 Polyunsaturated Fatty Acids on Offspring Sex-Ratio and Maternal Behavior in Mice. Biology of Reproduction, 78:211-217, 2008.
  • Shen H, Oesterling E, Stromberg A, Toborek M, MacDonald RS, Hennig B. Zinc deficiency induces vascular pro-inflammatory parameters associated with NF-kB and PPAR signaling. J Amer Coll Nutr 27:577-587, 2008.
  • Shenouda NS, Sakla MS, Newton LG, Besch-Williford C, Greenberg NM, MacDonald RS, Lubahn DB. Phytosterol Pygeum africanum regulates prostate cancer in vivo and in vitro. Endocrine 32:72-81, 2007.
  • Shen H, MacDonald RS, Bruemmer D, Stromberg A, Daugherty A, Li X, Toboreck M, Hennig B. Zinc Deficiency Alters Lipid Metabolism in LDL-Receptor-Deficient Mice Treated 2 with Rosiglitazone. J. Nutrition 137:2339-2345, 2007.
  • Sakla MS, Ansell PJ, Shenouda NS, Lubahn DB, MacDonald RS. Genistein Affects HER2 Protein Concentration, Activation and Promoter Regulation via Estrogen Receptor-and non-Estrogen Receptor-Mediated Mechanisms. Endocrine 32:69-78, 2007.
  • Wang Q, Simonyi A, Jensen MD, Shelat P, Rottinghaus GE, MacDonald R.S., Miller DK, Lubahn DB, Weisman GA, Sun AY, Sun GY. Curcumin Ameliorates Global Cerebral Ischemia-Induced Neuronal Apoptosis and Behavioral Deficits: Suppression of Oxidative Stress and Mitochondria Dysfunction. J. Neuroscience, 2005 82:138-148.
  • Wang Q, Simonyi A, Li W, Sisk BA, Miller RA, MacDonald, R.S., Lubahn DB, Sun GY, Sun AY. Dietary Grape Supplement Ameliorates cerebral ischemia-induced neuronal death in gerbils. Mol. Nut. Food Res. 2005 49:443-451.
  • Reiterer G, MacDonald R.S., Browning JD, Jr., Marrow J, Matveev SV, Daugherty A, Smart E, Toborek M, Hennig B. Zinc Deficiency Induces Atherogenic Events in LDL-Receptor Deficient Mice. J. Nutrition, 135(9):2114-8, 2005.
  • Guo, J.-Y., Li, X., Browning, J.D., Rottinghaus, G.E. and R.S. MacDonald. 2004. Soy isoflavones and estrone prevent colon cancer in mice. J. Nutrition, 134:179-182.
  • Curran, E.M., Judy, B.M., Newton, L.G., Lubahn, D.B., Rottinghaus, G.E., Macdonald, R.S., Franklin, C. and D.M. Estes. 2004. Dietary soy phytoestrogens and ERalpha signaling modulate interferon gamma production in response to bacterial infection. Clin & Exper Immun 2004 135(2):219-25.
  • Shenouda, N.S., Zhou, Q., Browning, J.D., Ansell, P.J., Sakla, M.S., Lubahn, D.B. and R.S. MacDonald. 2004. Phytoestrogens in Common Herbs Regulate Prostate Cancer Cell Growth in Vitro. Nutrition and Cancer 2004 49(2):200-208.
  • R.S. MacDonald. 2004. Regulation of Growth and the IGF System by Zinc. Invited book chapter, Nutrition and the IGF System, S. Houston editor, Human Press, 2004.
Food Science and Human Nutrition