Kevin Schalinske
Associate Professor/DOGE
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Education:
Ph.D., Nutritional Sciences, University of Wisconsin - Madison,
1992
Interests: Nutritional and hormonal regulation
of folate/ methyl group metabolism relevant to health and disease.
Office: 224C MacKay Hall
Phone: (515) 294-9230
Fax: (515) 294-6193
Email: kschalin@iastate.edu
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Publications:
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Schroeder, S.E., Reddy, M.B. & Schalinske, K.L. (2007) Retinoic acid modulates hepatic iron homeostasis in rats by attenuating the RNA-binding activity of iron regulatory proteins. J. Nutr., 137: 2686-2690, 2007
- Williams, K.T. & Schalinske, K.L (2007) New insights into the regulation of methyl group and homocysteine metabolism. J. Nutr 136: 311-314.
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Hartz, C.S. & Schalinske, K.L. (2006) Phosphatidylethanolamine N-methyltransferase and regulation of homocysteine metabolism. Nutr. Rev. 64: 465-467.
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Hartz, C.S., Nieman, K.M., Jacobs, R.L., Vance, D.E. & Schalinske, K.L. (2006) Hepatic phosphatidylethanolamine N-methyltransferase expression is increased in diabetic rats. J. Nutr 136: 3005-3009.
- Hanson, L.N., Engelman, H.M., Alekel, D.L., Schalinske, K.L., Kohut, M.L. & Reddy, M.B. (2006) Effects of soy isoflavones and phytate on homocysteine, C-reactive protein, and iron status in postmenopausal women. Am. J. Clin. Nutr. 84: 774-780.
- Nieman, K.M., Hartz, C.S., Szegedi, S.S., Garrow, T.A., Sparks, J.D. & Schalinske, K.L. (2006) Folate status modulates the induction of hepatic glycine N-methyltransferase and homocysteine metabolism in diabetic rats. Am. J. Physiol. Endocrinol. Metab. 291: E1235-E1242.
- Schalinske, K.L. & Nieman, K.M. (2005) Disruption of methyl
group metabolism by ethanol. Nutr. Rev.63: 387-391.
- Nieman, K.M., Rowling, M.J., Garrow, T.A. and K.L. Schalinske.
2004. Modulation of methyl group metabolism by streptozotocin-induced
diabetes and all-trans-retinoic acid. J. Biol. Chem. 279: 45708-45712.
- Tanghe, K.A., Garrow, T.A. and K.L. Schalinske. 2004. Triiodothyronine
treatment attenuates the induction of hepatic glycine N-methyltransferase
by retinoic acid and elevates plasma homocysteine concentrations in
rats. J. Nutr. J. Nutr. 134: 2913-2918.
- Ozias, M.K. and K.L. Schalinske. 2003. All-trans-retinoic acid rapidly
induces glycine N-methyltrasferase in a dose-dependent manner and
reduces circulating methionine and homocysteine levels in rats. J.
Nutr. 133: 4090-4094.
- Rowling, M.J. and K.L. Schalinske. 2003. Retinoic acid and glucocorticoid
treatment induces hepatic glycine N-methyltransferase and lowers plasma
homocysteine concentrations in the rat and rat hepatoma cells. J.
Nutr. 133: 3392-3398.
- K.L. Schalinske. 2003. Interrelationship between diabetes and homocysteine
metabolism: hormonal regulation of cystathionine β-synthase. Nutr.
Rev. 61: 136-138
- Rowling, M.J., McMullen, M.H., Chipman, D.C. and K.L. Schalinske.
2002. Hepatic glycine N-methyltransferase is up-regulated by methionine
in rats. J. Nutr. 132: 2545-2549.
- McMullen, M.H., Rowling, M.J., Ozias, M.K. and K.L. Schalinske.
2002. Activation and induction of glycine N-methyltransferase by retinoids
are tissue- and gender-specific. Arch. Biochem. Biophys. 401: 73-80.
- Rowling, M.J., McMullen, M.H. and K.L. Schalinske. 2002. Vitamin
A and its derivatives induce hepatic glycine N-methyltransferase and
hypomethylationof DNA in rats. J. Nutr. 132: 365-369.
- Rowling, M.J. and K.L. Schalinske. 2001. Retinoid compounds activate
and induce hepatic glycine N-methyltransferase in rats. J. Nutr. 131:
1914-1917.
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